Quick Answer: Is 400mg Of Modafinil Safe?

Is modafinil bad for your heart?

Modafinil substantially perturbs autonomic cardiovascular regulation by increase in heart rate and blood pressure.

Autonomic changes of this magnitude encourage caution in use of modafinil in patients with cardiovascular disease..

Is 400 mg of modafinil too much?

Modafinil (Provigil) is a wake-promoting drug approved for patients with narcolepsy or other causes of excessive daytime sleepiness. Each pill is 100 to 200 mg; maximal daily dose of modafinil in adults is 400 mg (the medication is not approved by the FDA for children younger than 16 years of age).

How many mg of modafinil should I take?

For narcolepsy or obstructive sleep apnea/hypopnea syndrome: Adults and teenagers 17 years of age and older—200 milligrams (mg) once a day, in the morning. Your doctor may increase your dose as needed. Teenagers and children younger than 17 years of age—Use and dose must be determined by your doctor.

How long modafinil kick in?

How long does it take to work? For most people, it usually takes 30 to 60 minutes to start working.

Can I take modafinil on empty stomach?

It is usually taken once a day with or without food. If you are taking modafinil to treat narcolepsy or OSAHS, you will probably take it in the morning. If you are taking modafinil to treat shift work sleep disorder, you will probably take it 1 hour before the beginning of your work shift.

Does modafinil show on drug tests?

It is free from interference by methylphenidate, cocaine, amphetamines and other drugs of abuse. The quantitation of excretion study samples shows that peak levels of modafinil could be found at 10 h both in GC-MS and LC-MS/MS analysis, which proves the authenticity of the method.

Is modafinil hard on the liver?

Hepatotoxicity. In clinical trials, modafinil and armodafinil were associated with a low rate of serum aminotransferase and alkaline phosphatase elevations (<1%). Furthermore, despite widescale use, there have not been reports of clinically apparent liver injury due to modafinil or armodafinil.

Can I take modafinil everyday?

The recommended dose for modafinil is 200mg taken once daily [23]. Modafinil has been found to be well-tolerated, with a low incidence of adverse effects and low potential for abuse [24].

Can you lose weight with modafinil?

Reinstitution of modafinil resulted in a 10-lb. weight loss over a 6-week period. Conclusions: Modafinil treatment resulted in a significant weight loss in this patient, possibly due to reducing clozapine-associated fatigue.

Does modafinil increase IQ?

However, interestingly, several interactions between modafinil and IQ emerged. Modafinil (100 and 200 mg) significantly improved target sensitivity in the RVIP test, but only in the group of ‘lower’ IQ (mean+/-sem=106+/-0.6), not in the ‘higher’ IQ group (mean+/-sem=115.5+/-0.5).

Can you drink alcohol on modafinil?

Do not drink alcohol while taking Modafinil as they can enhance each other’s side effects such as increased dehydration. Modafinil should be kept out of reach of children.

Can you build tolerance to modafinil?

There is no evidence that tolerance develops to modafinil or that the drug impairs sleep quality (if taken in the morning). It has a number of advantages including once-daily dosing, low abuse potential, and the fact that it is not a schedule II medication.

Can you take 600 mg of modafinil?

The safety data from this study suggest that the maximum tolerable single daily oral modafinil dose, without titration, may be 600 mg.

Can you overdose on modafinil?

Symptoms most often accompanying modafinil overdose, alone or in combination with other drugs have included: insomnia; central nervous system symptoms such as restlessness, disorientation, confusion, agitation, anxiety, excitation and hallucination; digestive changes such as nausea and diarrhoea; and cardiovascular …

How long does 200mg modafinil last?

Modafinil 200 mg adequately sustains performance at near baseline levels for up to 10 h. Despite early claims that modafinil does not interfere with sleep, results have shown that – similar to caffeine – modafinil impairs sleep if the sleep period is initiated within modafinil’s duration of action.